The facial nerve (CNVII) has two major divisions and controls the muscles of facial expression, including the frontalis muscle (raises the eyebrows), the orbicularis oculi muscle (closes the eyes), the zygomaticus muscles (raises the angle of the mouth)
Paresis of the orbicularis oculi muscle leads to a diminished blink, incomplete eyelid closure (Lagophthalmos), impairment of the nasolacrimal pumping system
The blink reflex and lid position are critical to maintain the ocular surface
Each blink spreads the tear film over the ocular surface and allows for a continuous layer of moisture.
Congenital
Moebius' Syndrome
Acquired
Bell's Palsy
vascular lesions
Tumors
Acoustic Neuroma
Parotid gland
temporal bone tumor
Trauma
Symptoms
Tearing, atonic eyelid
erms
Lagophthalmos: Patients with lagophthalmos have an inability to close eyelids. This may occur, for instance, in patients with Thyroid eye disease. Visit the lagophthalmos page
for more details.
Graves' disease is an autoimmune disease. It most commonly affects the thyroid, causing it to grow to twice its size or more (goiter), be overactive, with related hyperthyroid symptoms such as increased heartbeat, muscle weakness, disturbed sleep, and irritability. It can also affect the eyes, causing bulging eyes (exophthalmos). It affects other systems of the body, including the skin and reproductive organs. It affects up to 2% of the female population, often appears after childbirth, and has a female:male incidence of 5:1 to 10:1. It has a strong hereditary component; when one identical twin has Graves' disease, the other twin will have it 25% of the time. Smoking and exposure to second-hand smoke is associated with the eye manifestations but not the thyroid manifestations. Diagnosis is usually made on the basis of symptoms, although thyroid hormone tests may be useful, particularly to monitor treatment.