Sebaceous Carcinoma




Photo of Sebaceous Cell Carcinoma Photo of Sebaceous Cell Carcinoma
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Take a close look at this....Now go back and look at the chalazion. Always consider sebaceous cell carcinoma in the differential of recurring chalazion.

  • General
    • Sebaceous carcinoma is more common than squamous cell carcinoma.
    • It is rare in patients under 40 years of age. More common in females and Asians
  • Location
    • It occurs most commonly in the upper eyelid and is extremely rare elsewhere in the body. It can arise from meibomian glands, Zeis glands or sebaceous glands in caruncle.
  • Differential Diagnosis
    • It may mimic Chalazion or chronic blepharoconjunctivitis.
  • Factors associated with poor prognosis
    • Upper eyelid origin,
    • size greater than 10 millimeters
    • Meibomian gland origin
    • symptoms greater than 6 months
    • infiltrative growth pattern
    • pagetoid invasion
    • lymphatic or orbital invasion
  • Treatment
    • Wide local excision with frozen section control
Sebaceous Cell Carcinoma involving the right upper, lateral and lower eyelid.
Sebaceous Cell Carcinoma involving the right upper, lateral and lower eyelid.